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Zoryl M 2 mg/500mgTablet ER 20s
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Create ABHAIntroduction to Zoryl M 2 mg/500mgTablet ER 20s
Zoryl M 2mg/500mg Tablet ER is a combination medication containing Glimepiride (2mg) and Metformin (500mg). It is primarily used for the management of Type 2 Diabetes Mellitus (T2DM) by controlling blood sugar levels and improving insulin sensitivity.
How Zoryl M 2 mg/500mgTablet ER 20s works
Glimepiride (2mg): A sulfonylurea that stimulates the pancreas to produce more insulin, helping lower blood sugar levels. Metformin (500mg): A biguanide that reduces glucose production in the liver and enhances insulin sensitivity, improving glucose uptake by the muscles. Together, they help regulate blood sugar levels and reduce the risk of diabetes-related complications.
How To Use Zoryl M 2 mg/500mgTablet ER 20s
- Dosage: As prescribed by your doctor, usually once or twice daily.
- Administration: Swallow whole Zoryl M 2mg/500mg Tablet with water; do not crush or chew.
- With or Without Food: Best taken with meals to minimize stomach upset.
Special Precautions About Zoryl M 2 mg/500mgTablet ER 20s
- Inform your doctor if you have any known allergies to Glimepiride, Metformin, or other medications.
- Zoryl M 2mg/500mg Tablet ER may cause low blood sugar (hypoglycemia); monitor symptoms like dizziness or sweating.
- Regular blood sugar monitoring.
Benefits Of Zoryl M 2 mg/500mgTablet ER 20s
- Effectively controls blood sugar levels in Type 2 Diabetes.
- Reduces insulin resistance, improving glucose metabolism.
- Zoryl M 2mg/500mg Tablet ER prevents diabetes-related complications, such as nerve and kidney damage.
- Supports weight management in diabetic patients.
Side Effects Of Zoryl M 2 mg/500mgTablet ER 20s
- Common Side Effects: Nausea, vomiting, stomach upset, diarrhea.
- Moderate Side Effects: Weight gain, mild hypoglycemia, headache, dizziness.
- Severe Side Effects: Severe hypoglycemia (confusion, sweating, blurred vision), lactic acidosis, liver dysfunction.
What If I Missed A Dose Of Zoryl M 2 mg/500mgTablet ER 20s
- If you miss a dose, take it as soon as you remember.
- If it is almost time for your next dose, skip the missed dose.
- Do not double the dose to catch up.
Health And Lifestyle
Maintain a balanced diet rich in nutrients. Monitor your blood sugar levels regularly, and exercise regularly. Stay hydrated, manage stress, and avoid smoking and excessive alcohol.
Drug Interaction
- Beta-blockers (e.g., Atenolol) - May mask symptoms of hypoglycemia.
- Diuretics (e.g., Hydrochlorothiazide) - Can affect blood sugar control.
- Corticosteroids (e.g., Prednisolone) - May increase blood sugar levels.
- Antibiotics (e.g., Ciprofloxacin) - Can alter blood sugar levels.
Drug Food Interaction
- Avoid excessive alcohol consumption, as it may lead to lactic acidosis.
- High-fat meals may slow down the absorption of metformin.
- Maintain a balanced diet to prevent blood sugar fluctuations.
Disease Explanation
Type 2 Diabetes Mellitus (T2DM): A chronic condition in which the body either resists insulin or does not produce enough insulin, leading to high blood sugar levels. Insulin Resistance: A condition where body cells fail to respond to insulin effectively, causing blood sugar buildup. Hyperglycemia: High blood sugar levels that, if left uncontrolled, can cause long-term health issues.
Safety Advice for Zoryl M 2 mg/500mgTablet ER 20s
- High risk
- Moderate risk
- Safe
Use with caution if you have liver disease.
Use with caution if you have kidney disease.
Avoid alcohol consumption with Zoryl M 2mg/500mg Tablet ER as it can increase the risk of hypoglycemia and lactic acidosis.
Avoid driving if you experience dizziness or other side effects.
Not advised during pregnancy without medical supervision.
Consult your doctor before using this medication while breastfeeding.
Tips of Zoryl M 2 mg/500mgTablet ER 20s
- Take the tablet at the same time each day for consistent blood sugar control.
- Keep out of reach of children.
- Do not skip meals, as it may lead to low blood sugar.
FactBox of Zoryl M 2 mg/500mgTablet ER 20s
- Active Ingredients: Glimepiride (2mg), Metformin (500mg)
- Drug Class: Sulfonylurea + Biguanide
- Prescription: Required
- Route of Administration: Oral Tablet
- Available In: 20 tablets per pack
Storage of Zoryl M 2 mg/500mgTablet ER 20s
- Store at room temperature (15-25°C).
- Protect from moisture and heat.
- Keep away from children and pets.
Dosage of Zoryl M 2 mg/500mgTablet ER 20s
- As directed by the physician, typically one or two tablets per day.
Synopsis of Zoryl M 2 mg/500mgTablet ER 20s
Zoryl M 2mg/500mg Tablet ER is a combination anti-diabetic medication used to regulate blood sugar levels in Type 2 Diabetes patients. It improves insulin sensitivity, reduces glucose production, and enhances overall metabolic health.
FAQ's on Zoryl M 2 mg/500mgTablet ER 20s
Can the use of Zoryl M lead to lactic acidosis?
Yes, the use of Zoryl M can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Zoryl M and consult your doctor immediately.
Is it safe to take alcohol while I am also taking Zoryl M?
No, it is not safe to take Zoryl M along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.
What is Zoryl M?
Zoryl M is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Zoryl M?
The use of Zoryl M is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
Can the use of Zoryl M cause hypoglycemia?
Yes, the use of Zoryl M can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.
What are the recommended storage conditions for Zoryl M?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can the use of Zoryl M lead to Vitamin B12 deficiency?
Yes, the use of Zoryl M can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
What is Zoryl M Tablet used for?
It is used for managing Type 2 Diabetes Mellitus by lowering blood sugar levels.
How long does Zoryl M take to show effects?
It may take a few weeks to months for noticeable improvements in blood sugar control.
Can Zoryl M cause low blood sugar?
Yes, it may cause hypoglycemia; always monitor symptoms and carry a sugar source.
Can I take Zoryl M with insulin?
Yes, but under medical supervision to prevent excessive blood sugar reduction.
Does Zoryl M help in weight loss?
Metformin may support mild weight loss, but Glimepiride may cause slight weight gain.
Is Zoryl M safe for kidney patients?
Not recommended for severe kidney impairment.
Can I drink alcohol while taking Zoryl M?
Avoid alcohol as it increases the risk of lactic acidosis and hypoglycemia.
Can Zoryl M be used for Type 1 Diabetes?
No, it is only for Type 2 Diabetes.
What should I do if I experience dizziness?
Avoid standing up suddenly and drink water; consult your doctor if persistent.
Can I take Zoryl M on an empty stomach?
No, take it with meals to prevent stomach discomfort and low blood sugar.
Written By
Pranav ayush
MBA in Pharmaceutical
Content Updated on
Monday, 24 Feburary, 2025
