Tonoderm 5% Cream 15gm

This formula has been designed by combining five active constituents: Clobetasol propionate, Ketoconazole, Neomycin sulphate, Tolnaftate, Iodochlorhydroxyquinoline. Clobetasol propionate is a steroidal medicine that causes redness in the skin by blocking the production of certain chemical messengers (prostaglandins); reduce itching and swelling. Ketoconazole damages the fungal cell membrane and this membrane is necessary for the survival of the fungus. Neomycin sulphate is an antibiotic that inhibits the growth of bacteria by preventing the synthesis of essential proteins that are necessary for bacteria to perform vital functions. Tolnaftate is an antifungal agent that inhibits fungal growth by inhibiting the squalene epoxidase enzyme (crucial for synthesis of fungal cell membrane) and leads to cell death. Iodochlorhydroxyquinoline have a broad-spectrum antimicrobial activity which disrupt cell-membrane of cell membranes and inhibits vital enzyme systems, lead to prevention and treatment of bacterial and fungal skin infections.

• Before applying it, clean and dry the affected area
• Apply a thin layer of the formula on the infected skin, rub it gently
• Use two times in a day, or as suggested by your director
• Avoid contact with eyes and mucous membranes
• After applying it, wash your hands thoroughly if they are not affected

• Avoid contact with eyes, mucous membranes, or open wounds Rinse thoroughly with water if accidental contact occurs
• Use this medication as directed by your healthcare provider Avoid excessive use or prolonged application without medical supervision
• Do not apply this medication on broken or irritated skin without consulting a healthcare professional
• If you experience severe skin irritation, allergic reactions, or worsening of symptoms, discontinue use and consult your doctor

• Beneficial in reducing wrinkles on skin and make skin moisturise

• Burning
• Redness
• Irritation
• Cracks on skin
• Itching
• Thinning of skin
• Allergy